Neuroscientists at Duke Health have developed a brain-machine interface (BMI) that allows primates to use only their thoughts to navigate a robotic wheelchair.
The BMI uses signals from hundreds of neurons recorded simultaneously in two regions of the monkeys’ brains that are involved in movement and sensation. As the animals think about moving toward their goal — in this case, a bowl containing fresh grapes — computers translate their brain activity into real-time operation of the wheelchair.
The interface, described in the March 3 issue of the online journal Scientific Reports, demonstrates the future potential for people with disabilities who have lost most muscle control and mobility due to quadriplegia or ALS, said senior author Miguel Nicolelis, M.D., Ph.D., co-director for the Duke Center for Neuroengineering.
“In some severely disabled people, even blinking is not possible,” Nicolelis said. “For them, using a wheelchair or device controlled by noninvasive measures like an EEG (a device that monitors brain waves through electrodes on the scalp) may not be sufficient. We show clearly that if you have intracranial implants, you get better control of a wheelchair than with noninvasive devices.”
Scientists began the experiments in 2012, implanting hundreds of hair-thin microfilaments in the…